This is a new one for me. HCG will spike your test, which can convert to estrogen. I suppose that when you are manipulating hormones, there is always a chance that it can have an effect on your emotions. If you have had this happen more than once, it might be more than a coincidence. If you are not using an AI, you might want to see if taking a little adex will make any difference. Otherwise, you might want to consider lowering the dose and see if thats any better. If you are taking 250iu, 2x wk, through your cycle, maybe reduce it by 50% per shot and see if you do better. Maybe a lower dose, more often might keep things from fluctuating too much