Whenever you combine 2 compounds at standard doses into 1cc, there is probably going to be more pain. Thats a lot of total mg's for 1ml of oil which makes the chance of pain go way up and the solvents will have to be higher, which can also cause irritation and inflammation. IMO, you are much better off using traditional single hormone gear for the majority of a cycle. I stick with mostly traditional gear and if I use a blend, it is going to be a small amount. I may use Test E and EQ, taken ED or EOD and then add in 1/2cc EOD of a blend to push the MG's up. When I add 1/2cc of a blend to a shot that was already 2cc, and make sure that that the gear is all mixed together in the barrel before injecting, I get little to no pain.
Another option would be to cut the blend with sterile oil. This can work well.
Also, slightly warming the gear will help it absorb into the muscle
Finally, make sure to rotate sites and stick with larger muscles. Glutes work best.