Estrogen is high brother! 50 is the high end of normal, but I would try to maintain it even lower than that. You need to get that under control. I would start with .5mg arimidex 3x wk and see how you feel after a week. I suspect you will feel way better within a few days and on track within 10 days. If you feel like you are still off at that point, go to .5mg EOD. Eventually, I would get some labs done again