Hey again brother, sure, Insulin would work fine with any cycle, as long as it fits your goals. You don't have to pick specific AAS to use insulin. It's working in a totally different way. As for NPP and recovery, I believe it is easier to recover from. It doesn't build up as high in your system and I think this makes a difference
As for homeostasis, you are on to something. Changing out compounds or upping doses are ways to keep your body responding. Another major issue...probably even bigger, is decreased insulin sensitivity over time. You can't just continue to cram more food in to keep growing. Sometimes, this means dialing carbs back and coming off of insulin. Maybe using GDAs during this time. I might run insulin for 8 wks, Then off for 4 and run a "mini" diet", reducing carbs a little and eating very clean, then 8 wks back on insulin.