This is not the norm, but it isn't unheard of. I have a buddy that has the worst response to growth. 2iu's will bloat him up something awful, like we are taking 10-15 lbs of water in a wk, all sub q. He looks and feels like crap. Some guys just have a poor response. I would suggest taking even less and breaking your dose up. Over time, you may get used to it and be able to increase some. Even if you can work up to 2iu comfortably, you'll get a good response for fat loss and a positive push toward optimal muscle gain, plus of course all the health benefits like improved hair, nails and skin. So maybe start with just .5iu a day. Then after a couple weeks, maybe go to 2 shots of .4iu a day. Then after a couple wks, 2 shots of .5iu. You can see where I'm going with this. Just take your time. Even if this is as much as you can tollerate, it's going to be better than nothing. And really for pharm grade GH, 1.5-2iu is going to be more like 3-4 of some of the generics.