I think that starting lower and see how she does. so yea, about 25mg ED, then increase to 50mg but Keep in mind that oral primo really is not that great. I'm pretty conservative when it comes to females and I'm saying that it really is not that awesome. After Var, I would opt for injectable primo, even if she wanted to start very low. She can load it into an insulin pin and break down the dose quite small. I would try 50mg, which is a standard intro dose. If she wanted, you could even do less. If she finds 50mg ok and wants to increase, then go to 75mg. 100mg is a standard "normal" dose for a female. just make sure you go with a good brand like Geneza. My gal has used it a couple times and I trust them. I have had several clients use GP too, so thats my suggestion.