Adex is anti aromatase medication. We refer to these as an AI. Test converts to estregen. Adex stops/slows this conversion from happening. Nolvadex is a blocker. It will bind to some of the same receptors that estrogen would bind to. So Nolvadex does nothing to lower estreogen. It just stops it from binding to certain areas of your body. You can still have very high E while on Nolvadex and still suffer effects of high e like water and fat retention, acne, etc, even if the nolva is keeping you from getting gyno. So we want to use an AI like adex to prevent e from being a proble to begin with. It usually comes in 1mg tabs and you can break them in half if you want to take less. The dose you need will be individual. Some guys need more, some need less. .5mg EOD to 1mg ED is average depending on the person and the gear dose. Nolvadex is good to have on hand if your E gets too high and you begin to get gyno. Take the nolva while you increase the adex. Over time, E levels will go down and the nolva will keep you safe during that time. Hope this helps!