EPO is one thing I have never personally used or advised people on. Since it can kill you, I wouldn't feel comfortable giving advise. I will say be careful with it and I would rethink the anadrol. That can greatly increase RBC to dangerous levels on its own when you used high enough long enough. Thats also the reason I have not used EPO. I can get RBC high without it. From what I understand from the medication insert, there is not a set dose. They just keep monitoring blood levels every day to ensure you don't go too high. I guess it can happen fast, like day to day and if your blood is too thick, you can have a stroke. Basically, too much and your blood turns to sludge and cant be pumped. So that said, please just be careful and use caution. Continue to read and research unit you are confident.