Hey bro, I am personally not a fan of super high dosed gear. That much hormone isn't designed to be put into such a small amount of oil. The only way I can suggest using it is for guys that are high dose users, looking to boost their total mg, maybe adding a 1/2cc in here and there, into a larger shot of gear with a normal concentration. So say you are using a shot that contains 200mg EQ, 100mg Mast E and 125mg of traditionally brewed test, I can see squeezing in 1/2cc of T400, which will now take that shot up to 325mg. When done like this, the pain is going to be lower. But I would not use it as my stand alone test.